Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4228728 | 0.93 | PKM (0.38) | MCHR1PKMKDRMCHR2MAPT | |
| SCHEMBL4236329 | 0.93 | PKM (0.38) | MCHR1PKMMCHR2NAMPTMAPT | |
| SCHEMBL4237744 | 0.93 | PKM (0.38) | MCHR1PKMMCHR2NAMPTMAPT | |
| SCHEMBL4228886 | 0.92 | PKM (0.40) | MCHR1PKMKDRBRAFMCHR2 | |
| SCHEMBL4226989 | 0.90 | TAS1R3 (0.39) | MCHR1PKMKDRTAS1R3TAS1R1 | |
| SCHEMBL4233302 | 0.89 | PKM (0.38) | MCHR1PKMKDRBRAFMCHR2 | |
| SCHEMBL4239015 | 0.86 | PKM (0.43) | MCHR1PKMMCHR2NAMPTMAPT | |
| SCHEMBL4238833 | 0.86 | PKM (0.38) | MCHR1PKMMCHR2MAPTTAS1R3 | |
| SCHEMBL4229247 | 0.85 | MCHR1 (0.45) | MCHR1PKMNAMPTTAS1R3TAS1R1 | |
| SCHEMBL4237676 | 0.85 | PNLIP (0.41) | MCHR1PKMMCHR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |