Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 9/20 | 0.48 |
| ▸ | PLAU | P00749 | 3/20 | 0.48 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784404 | 0.88 | SLC9A1 (0.51) | SLC9A1SLC9A5 | |
| SCHEMBL4786226 | 0.84 | SLC9A1 (0.52) | SLC9A1 | |
| SCHEMBL2682845 | 0.83 | CYP1A2 (0.55) | CYP1A2DHODHPTGER1 | |
| SCHEMBL4788479 | 0.81 | SLC9A1 (0.49) | SLC9A1 | |
| SCHEMBL11312831 | 0.80 | CYP1A2 (0.58) | CYP1A2DHODHPTGER1 | |
| SCHEMBL4787618 | 0.75 | CYP1A2 (0.47) | CYP1A2DHODHPTGER1 | |
| Hydrochloric Acid SCHEMBL6312712 | 0.74 | PLAU (0.47) | SLC9A1PLAUSLC9A2ASIC3 | |
| SCHEMBL4787413 | 0.73 | TP53 (0.51) | SLC9A1SLC9A5 | |
| SCHEMBL4786806 | 0.71 | ALDH1A1 (0.48) | SLC9A1 | |
| Hydrochloric Acid SCHEMBL6313857 | 0.70 | PLAU (0.52) | SLC9A1PLAUSLC9A2ASIC3SLC9A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008111794-A1 | 4-METHYLIMIDAZOL-5-YLCARBONYLGUANIDINE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF THE ISCHEMIC HEART DISEASES CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-09-18 | — | — | WO | disclosed |