Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 12/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 2/20 | 0.40 |
| ▸ | ATP4B | P51164 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786226 | 0.89 | SLC9A1 (0.52) | SLC9A1 | |
| SCHEMBL4787624 | 0.88 | CYP1A2 (0.49) | SLC9A1SLC9A5 | |
| SCHEMBL4787413 | 0.80 | TP53 (0.51) | SLC9A1BACE1SLC9A5 | |
| SCHEMBL4784399 | 0.77 | RAB9A (0.38) | SLC9A1TLR8 | |
| SCHEMBL4788479 | 0.75 | SLC9A1 (0.49) | SLC9A1BACE1 | |
| Hydrochloric Acid SCHEMBL7830653 | 0.72 | SLC9A1 (0.58) | SLC9A1BACE1 | |
| SCHEMBL2682845 | 0.71 | CYP1A2 (0.55) | — | |
| SCHEMBL4786806 | 0.71 | ALDH1A1 (0.48) | SLC9A1BACE1 | |
| SCHEMBL29171117 | 0.70 | RAB9A (0.46) | — | |
| SCHEMBL30785610 | 0.70 | RAB9A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008111794-A1 | 4-METHYLIMIDAZOL-5-YLCARBONYLGUANIDINE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF THE ISCHEMIC HEART DISEASES CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-09-18 | — | — | WO | disclosed |