Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | FABP1 | P07148 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785450 | 0.91 | CCR1 (0.46) | L3MBTL1MAPTTSHRALOX15MAPK1 | |
| SCHEMBL4788145 | 0.88 | CCR1 (0.43) | L3MBTL1MAPTTSHRALOX15MAPK1 | |
| SCHEMBL4786573 | 0.88 | CCR1 (0.43) | L3MBTL1MAPTTSHRALOX15MAPK1 | |
| SCHEMBL4807717 | 0.88 | MAPT (0.48) | L3MBTL1MAPTTSHRALOX15MAPK1 | |
| SCHEMBL4785395 | 0.82 | MAPT (0.55) | MAPTTSHRMAPK1HTTSMN1; SMN2 | |
| SCHEMBL4788034 | 0.81 | ALDH1A1 (0.59) | MAPTMAPK1CCR1ALDH1A1 | |
| SCHEMBL4786322 | 0.79 | PKLR (0.45) | L3MBTL1MAPTTSHRALOX15MAPK1 | |
| SCHEMBL4788589 | 0.79 | PKLR (0.45) | L3MBTL1MAPTMAPK1ALDH1A1GAA | |
| SCHEMBL8156622 | 0.79 | EPHX2 (0.47) | L3MBTL1MAPTTSHRALOX15MAPK1 | |
| SCHEMBL4786465 | 0.79 | PKLR (0.47) | L3MBTL1MAPTMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | disclosed |