Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | CCR1 | P32246 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785395 | 0.85 | MAPT (0.55) | ALDH1A1KMT2AMEN1CCR1MAPT | |
| SCHEMBL4787844 | 0.81 | L3MBTL1 (0.50) | ALDH1A1CCR1MAPTMAPK1 | |
| SCHEMBL4785450 | 0.80 | CCR1 (0.46) | ALDH1A1KMT2AMEN1CCR1MAPT | |
| SCHEMBL4786636 | 0.78 | CCR1 (0.44) | ALDH1A1KMT2AMEN1CCR1MAPT | |
| SCHEMBL4788145 | 0.77 | CCR1 (0.43) | ALDH1A1CCR1MAPTLMNAMAPK1 | |
| SCHEMBL4786573 | 0.77 | CCR1 (0.43) | ALDH1A1KMT2AMEN1CCR1MAPT | |
| SCHEMBL4807717 | 0.77 | MAPT (0.48) | ALDH1A1KMT2AMEN1CCR1MAPT | |
| SCHEMBL5290681 | 0.76 | CCR1 (0.46) | ALDH1A1KMT2AMEN1CCR1MAPT | |
| SCHEMBL5246794 | 0.76 | TRPV4 (0.47) | ALDH1A1KMT2AMEN1CCR1MAPT | |
| SCHEMBL4816303 | 0.76 | CCR1 (0.46) | ALDH1A1KMT2AMEN1CCR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | disclosed |