SCHEMBL4788337

SCHEMBL4788337

Cc1ccc(-[n+]2ccc(-c3ccncc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 1/20 0.50
APOBEC3A P31941 1/20 0.50
EIF4H Q15056 1/20 0.50
APOBEC3G Q9HC16 1/20 0.50
MAPT P10636 3/20 0.44
LMNA P02545 1/20 0.44
RAB9A P51151 5/20 0.40
NPC1 O15118 4/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
KDM4E B2RXH2 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HSD17B10 Q99714 2/20 0.40
ALDH1A1 P00352 2/20 0.39
TP53 P04637 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
STAT1 P42224 1/20 0.39
NOTUM Q6P988 1/20 0.38
FLT3 P36888 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4818348 0.98 PABPC1 (0.48) PABPC1APOBEC3AEIF4HAPOBEC3GMAPT
Hydrochloric Acid SCHEMBL2469434 0.89 RAB9A (0.42) PABPC1APOBEC3AEIF4HAPOBEC3GMAPT
SCHEMBL12216504 0.87 MAPT (0.52) PABPC1APOBEC3AEIF4HAPOBEC3GMAPT
SCHEMBL12267700 0.87 ACHE (0.43) MAPTRAB9ANPC1KDM4EALDH1A1
Hydrochloric Acid SCHEMBL2464575 0.82 PABPC1 (0.47) PABPC1APOBEC3AEIF4HAPOBEC3GRAB9A
SCHEMBL10439878 0.80 MAPT (0.46) PABPC1APOBEC3AEIF4HAPOBEC3GMAPT
SCHEMBL14528749 0.80 NOTUM (0.60) PABPC1APOBEC3AEIF4HAPOBEC3GMAPT
SCHEMBL13918083 0.79 KDM4E (0.51) PABPC1APOBEC3AEIF4HAPOBEC3GLMNA
SCHEMBL23058911 0.79 SLC22A2 (0.48) MAPTLMNARAB9ANPC1SMN1; SMN2
SCHEMBL17384312 0.79 SLC22A2 (0.48) PABPC1APOBEC3AEIF4HAPOBEC3GBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009000547-A2 ELECTROCHROMIC DEVICE WITH IMPROVED VIOLOGEN ADSORPTION AND INKS FOR MAKING SAME NTERA LIMITED (IE) 2008-12-31 WO disclosed