Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 3/20 | 0.34 |
| ▸ | ARG2 | P78540 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457409 | 0.83 | ARG1 (0.34) | ARG1ARG2 | |
| SCHEMBL28122816 | 0.82 | — | — | |
| SCHEMBL9801094 | 0.81 | CA1 (0.38) | ARG1ARG2 | |
| SCHEMBL9801522 | 0.78 | TDP1 (0.44) | ARG1ARG2 | |
| SCHEMBL11453063 | 0.77 | TRPA1 (0.35) | ARG1ARG2 | |
| SCHEMBL9801020 | 0.76 | — | — | |
| SCHEMBL9801310 | 0.75 | CA1 (0.41) | — | |
| SCHEMBL11461027 | 0.75 | SIGMAR1 (0.36) | ARG1ARG2 | |
| SCHEMBL9801355 | 0.74 | CA1 (0.39) | — | |
| SCHEMBL9801609 | 0.72 | CYP1A2 (0.41) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124582-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |