Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.72 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | EDNRB | P24530 | 2/20 | 0.49 |
| ▸ | EDNRA | P25101 | 2/20 | 0.49 |
| ▸ | TNKS | O95271 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751583 | 0.84 | PTGS2 (1.00) | PTGS2PTPRCEDNRBEDNRATNKS | |
| SCHEMBL30009937 | 0.77 | PTGS2 (0.66) | PTGS2PTPRCGSK3AGSK3BMEN1 | |
| SCHEMBL404584 | 0.77 | PTGS2 (0.66) | PTGS2PTPRCGSK3AGSK3BMEN1 | |
| SCHEMBL6316764 | 0.76 | PTGS2 (0.87) | PTGS2PTPRCEDNRBEDNRATNKS | |
| SCHEMBL114611 | 0.75 | PTGS2 (0.67) | PTGS2GSK3B | |
| SCHEMBL9474080 | 0.73 | PTGS2 (0.64) | PTGS2GSK3B | |
| SCHEMBL8700474 | 0.72 | PTGS2 (0.77) | PTGS2PTPRCEDNRBEDNRATNKS | |
| SCHEMBL6757588 | 0.72 | PTGS2 (0.55) | PTGS2PTPRCTNKSPARP1TNKS2 | |
| SCHEMBL2692579 | 0.72 | CA12 (0.59) | PTGS2PTPRCMEN1KMT2ANPC1 | |
| SCHEMBL29629010 | 0.72 | PTGS2 (0.58) | PTGS2PTPRCMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140251-A2 | CYCLOOXYGENASE-2 INHIBITORS | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2008-11-20 | — | — | WO | disclosed |
| WO-2008140251-A2 | CYCLOOXYGENASE-2 INHIBITORS | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2008-11-20 | — | — | WO | disclosed |