Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4444936 | 0.87 | BCAT2 (0.53) | BCAT2MEN1KMT2AKDM4EBRD4 | |
| SCHEMBL31255442 | 0.84 | BCAT2 (0.42) | BCAT2MEN1KMT2AIKBKBGAA | |
| SCHEMBL4439618 | 0.81 | BCAT2 (0.62) | BCAT2MEN1KMT2ABRD4IKBKB | |
| SCHEMBL4881197 | 0.80 | BCAT2 (0.60) | BCAT2MEN1KMT2AKDM4EBRD4 | |
| SCHEMBL4434802 | 0.79 | BCAT2 (0.43) | BCAT2MEN1KMT2AGAAPLA2G2A | |
| SCHEMBL28149292 | 0.78 | BCAT2 (0.50) | BCAT2MEN1KMT2AKDM4EBRD4 | |
| SCHEMBL11649470 | 0.77 | BCAT2 (0.49) | BCAT2MEN1KMT2AKDM4EBRD4 | |
| SCHEMBL4143761 | 0.77 | BCAT2 (0.56) | BCAT2MEN1KMT2AKDM4EBRD4 | |
| SCHEMBL4155497 | 0.76 | PKM (0.36) | MEN1KMT2AKDM4EGAACCNC | |
| SCHEMBL4065289 | 0.76 | BCAT2 (0.43) | BCAT2MEN1KMT2AKDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119772-A1 | AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES | MEDIVIR AB (SE) | 2008-10-09 | — | — | WO | disclosed |