Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 8/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772701 | 0.80 | ALDH1A1 (0.36) | GNAI3GNAO1GNAI1MAPTTHRB | |
| SCHEMBL4552184 | 0.80 | HPGD (0.47) | MAPTTHRBPKM | |
| SCHEMBL11810128 | 0.75 | — | — | |
| SCHEMBL9029595 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL27793328 | 0.74 | GNAI3 (0.53) | GNAI3GNAO1GNAI1POLBMAPT | |
| SCHEMBL15270730 | 0.73 | THRB (0.40) | GNAI3GNAO1GNAI1POLBMAPT | |
| SCHEMBL15271904 | 0.73 | THRB (0.40) | GNAI3GNAO1GNAI1POLBMAPT | |
| SCHEMBL15271476 | 0.73 | THRB (0.40) | GNAI3GNAO1GNAI1POLBMAPT | |
| SCHEMBL16413053 | 0.73 | THRB (0.40) | GNAI3GNAO1GNAI1POLBMAPT | |
| SCHEMBL15271194 | 0.73 | THRB (0.40) | GNAI3GNAO1GNAI1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121592-A2 | ACETYL COENZYME A CARBOXYLASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-10-09 | — | — | WO | disclosed |