Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.54 |
| ▸ | NPC1 | O15118 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.54 |
| ▸ | RELA | Q04206 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 10/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 2/20 | 0.47 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788526 | 1.00 | RAB9A (0.54) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL4788532 | 1.00 | RAB9A (0.54) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL14041986 | 0.87 | GSTO1 (0.51) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL4787782 | 0.84 | RAB9A (0.59) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL4787776 | 0.84 | RAB9A (0.59) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL4788550 | 0.81 | MAPT (0.55) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL4788555 | 0.81 | MAPT (0.55) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL4788558 | 0.81 | MAPT (0.55) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL4746933 | 0.78 | SMN1; SMN2 (0.59) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL4746942 | 0.78 | SMN1; SMN2 (0.59) | RAB9ASMN1; SMN2NPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | claimed |
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | disclosed |