Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789170 | 0.87 | RAB9A (0.54) | GSTO1LMNARAB9AMAPK1ALDH1A1 | |
| SCHEMBL4788532 | 0.87 | RAB9A (0.54) | GSTO1LMNARAB9AMAPK1ALDH1A1 | |
| SCHEMBL4788526 | 0.87 | RAB9A (0.54) | GSTO1LMNARAB9AMAPK1ALDH1A1 | |
| SCHEMBL4787914 | 0.84 | ADORA3 (0.64) | LMNARAB9AMAPK1ALDH1A1NPC1 | |
| SCHEMBL4788550 | 0.79 | MAPT (0.55) | GSTO1LMNARAB9AMAPK1ALDH1A1 | |
| SCHEMBL4788558 | 0.79 | MAPT (0.55) | GSTO1LMNARAB9AMAPK1ALDH1A1 | |
| SCHEMBL4788555 | 0.79 | MAPT (0.55) | GSTO1LMNARAB9AMAPK1ALDH1A1 | |
| SCHEMBL4750340 | 0.77 | KDM4E (0.53) | GSTO1LMNARAB9AMAPK1ALDH1A1 | |
| SCHEMBL4750343 | 0.77 | KDM4E (0.53) | GSTO1LMNARAB9AMAPK1ALDH1A1 | |
| SCHEMBL14042493 | 0.74 | MAPT (0.61) | LMNAMAPK1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124000-A2 | THIAZOLE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2008-10-16 | — | — | WO | disclosed |