Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789624 | 0.90 | HSD17B10 (0.46) | HSD17B10GAAHCAR3KDM4EL3MBTL1 | |
| SCHEMBL14023660 | 0.82 | NPSR1 (0.36) | GAAKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL14023608 | 0.82 | MAPK8 (0.39) | GAAKDM4EL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL14023674 | 0.82 | ALDH1A1 (0.37) | GAAKDM4ENPSR1MEN1NPC1 | |
| SCHEMBL14023791 | 0.82 | KDM4E (0.44) | GAAKDM4ENPSR1MEN1KMT2A | |
| SCHEMBL14023630 | 0.81 | GAA (0.44) | HSD17B10GAAHCAR3L3MBTL1NPSR1 | |
| SCHEMBL14023587 | 0.81 | NPC1 (0.51) | HSD17B10GAAKDM4EPARP1MEN1 | |
| SCHEMBL4789623 | 0.80 | G6PD (0.43) | HSD17B10KDM4ENPSR1ALDH1A1HPGD | |
| SCHEMBL14023601 | 0.80 | MEN1 (0.46) | GAAKDM4EL3MBTL1NPSR1MEN1 | |
| SCHEMBL4788945 | 0.78 | ALDH1A1 (0.48) | KDM4EL3MBTL1NPSR1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141385-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008141385-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2008-11-27 | — | — | WO | disclosed |