Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 2/20 | 0.43 |
| ▸ | TDP2 | O95551 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | LITAF | Q99732 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | USP14 | P54578 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14023660 | 0.81 | NPSR1 (0.36) | ALDH1A1NPSR1GRM4KDM4ETSHR | |
| SCHEMBL14023608 | 0.81 | MAPK8 (0.39) | ALDH1A1NPSR1KDM4EPOLB | |
| SCHEMBL14023674 | 0.81 | ALDH1A1 (0.37) | ALDH1A1NPSR1OPRM1OPRD1OPRK1 | |
| SCHEMBL14023791 | 0.81 | KDM4E (0.44) | ALDH1A1NPSR1GRM4KDM4ETSHR | |
| SCHEMBL4789265 | 0.80 | HSD17B10 (0.43) | ALDH1A1NPSR1OGFRL1KDM4EHSD17B10 | |
| SCHEMBL4789298 | 0.78 | TDP2 (0.45) | TDP2ALDH1A1KDM4EHPGD | |
| SCHEMBL14023720 | 0.78 | TNF (0.40) | G6PDALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL4787936 | 0.77 | KDM4E (0.41) | TDP2ALDH1A1NPSR1CA1CA2 | |
| SCHEMBL14023663 | 0.74 | NPSR1 (0.35) | ALDH1A1NPSR1GRM4OPRM1OPRK1 | |
| SCHEMBL4789624 | 0.72 | HSD17B10 (0.46) | NPSR1OGFRL1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141385-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008141385-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2008-11-27 | — | — | WO | disclosed |