Propylene Oxide

Propylene Oxide

SCHEMBL4789591

CC1CO1.OCC(O)COCC(O)CO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.42
KDM4E B2RXH2 3/20 0.34
LMNA P02545 3/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 2/20 0.32
AGTR1 P30556 1/20 0.32
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Oxide SCHEMBL11765309 0.94 USP2 (0.39) USP2KDM4ELMNADUSP3MEN1
Propylene Oxide SCHEMBL28924060 0.88 USP2 (0.46) USP2LMNAALDH1A1CYP1A2AGTR1
Propylene Oxide SCHEMBL28054099 0.87 USP2 (0.34) USP2KDM4ELMNAALDH1A1CYP1A2
Glycerin SCHEMBL2936531 0.84 LMNA (0.50) LMNAALDH1A1
Glycerin SCHEMBL286713 0.84 LMNA (0.50) LMNAALDH1A1
Glycerin SCHEMBL27324317 0.82 LMNA (0.43) LMNAALDH1A1
Glycerin SCHEMBL2357917 0.81 ALDH1A1 (0.38) USP2LMNAALDH1A1
Propylene Oxide SCHEMBL28155714 0.80 KDM4E (0.31) USP2KDM4ELMNADUSP3MEN1
Glycerin SCHEMBL28366358 0.79 LMNA (0.45) LMNAALDH1A1
SCHEMBL27870592 0.79 TSHR (0.43) USP2KDM4ELMNAALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4032485-A POLYURETHANE FOAMS BASED ON MIXED ITACONIC ACID POLYESTERS MIYOSHI YUSHI KABUSHIKI KAISHA (JA) 1977-06-28 US claimed
CN-111621409-A System and method for preparing microbial activation microbial inoculum for river pollution treatment 湖南艾布鲁环保科技股份有限公司 2020-09-04 CN disclosed
CN-108126675-B Porous adsorbent with polyamine-expressed surface, and preparation method and application thereof 同济大学 2020-08-18 CN disclosed
CN-110157311-A Aqueous double-formulation polyurethane coating composition 关西涂料株式会社 2019-08-23 CN disclosed
CN-105925222-A Environment-friendly epoxy resin adhesive with good heat stability and long storage time 合肥东彩印刷科技有限公司 2016-09-07 CN disclosed
CN-105778351-A Antibacterial polyvinyl chloride plastic tube and preparation method thereof 安徽玉发塑业有限公司 2016-07-20 CN disclosed
CN-105377983-A Polybutylene terephthalate resin composition and injection-molded article WINTECH POLYMER LTD 2016-03-02 CN disclosed
CN-104342000-A Heat-preservation and thermal-insulating water-based paint for glass sliding door and preparation method of water-based paint FENGYANG HUIHENG TRADING CO LTD 2015-02-11 CN disclosed
EP-1060733-B1 Hairdressing cosmetic preparation and hairdressing method using the same SHISEIDO CO LTD (JP) 2008-02-13 EP disclosed
US-6649154-B1 Hairdressing cosmetic preparation and hairdressing method using the same SHISEIDO CO., LTD. (JP) 2003-11-18 US disclosed
CN-1374852-A Hair care compositions containing alkyl ethoxylates and methods of forming the same PROCTER & GAMBLE (US) 2002-10-16 CN disclosed
EP-1060733-A2 Hairdressing cosmetic preparation and hairdressing method using the same SHISEIDO COMPANY LIMITED (JP) 2000-12-20 EP disclosed
US-4151269-A ETHYLENE OXIDE, PROPYLENE OXIDE, POLYOL, POLYETHERS SHISEIDO CO., LTD. (JP) 1979-04-24 US disclosed
US-4032485-A POLYURETHANE FOAMS BASED ON MIXED ITACONIC ACID POLYESTERS MIYOSHI YUSHI KABUSHIKI KAISHA (JA) 1977-06-28 US disclosed