SCHEMBL4789923 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	CHRM3	P20309	12/20	0.39

▸	CHRM2	P08172	2/20	0.35

▸	CHRM1	P11229	2/20	0.35

▸	ALDH1A1	P00352	1/20	0.34

▸	TSHR	P16473	1/20	0.34

▸	TAAR1	Q96RJ0	1/20	0.34

▸	TRPM8	Q7Z2W7	1/20	0.34

▸	CALM1	P0DP23	1/20	0.33

▸	CTSL	P07711	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4788059	0.89	CHRM3 (0.37)	CHRM3ALDH1A1TSHRTAAR1TRPM8
SCHEMBL4789383	0.89	CHRM3 (0.36)	CHRM3CHRM2CHRM1ALDH1A1TSHR
SCHEMBL4787715	0.87	CYP1A2 (0.38)	CHRM3CHRM2CHRM1ALDH1A1TSHR
SCHEMBL4789938	0.85	KDM4E (0.35)	CHRM3ALDH1A1TSHRTAAR1TRPM8
SCHEMBL4789357	0.85	POLB (0.35)	CHRM3ALDH1A1TSHRTAAR1TRPM8
SCHEMBL4788471	0.85	CHRM3 (0.37)	CHRM3CHRM2CHRM1ALDH1A1TSHR
SCHEMBL4788452	0.81	TSHR (0.36)	CHRM3ALDH1A1TSHRTAAR1TRPM8
SCHEMBL4790212	0.79	MAPT (0.36)	CHRM3ALDH1A1TSHRTAAR1TRPM8
SCHEMBL4788570	0.79	CHRM3 (0.38)	CHRM3CHRM2CHRM1ALDH1A1TSHR
SCHEMBL4790238	0.78	ALDH1A1 (0.35)	CHRM3ALDH1A1TSHRTAAR1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008117229-A1	MUSCARINIC RECEPTOR ANTAGONISTS	RANBAXY LABORATORIES LIMITED (IN)	2008-10-02	—	—	WO	disclosed