Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788059 | 0.94 | CHRM3 (0.37) | TSHRCHRM3ALDH1A1TRPM8TAAR1 | |
| SCHEMBL4789938 | 0.91 | KDM4E (0.35) | TSHRCHRM3ALDH1A1TRPM8TAAR1 | |
| SCHEMBL4789177 | 0.91 | CCR3 (0.33) | POLBTSHRALDH1A1TRPM8HSP90AA1 | |
| SCHEMBL4789676 | 0.89 | POLB (0.32) | POLBTSHRALDH1A1TRPM8HSP90AA1 | |
| SCHEMBL4789954 | 0.88 | CHRM3 (0.34) | POLBTSHRCHRM3ALDH1A1TRPM8 | |
| SCHEMBL4789383 | 0.87 | CHRM3 (0.36) | TSHRCHRM3ALDH1A1TRPM8TAAR1 | |
| SCHEMBL4789922 | 0.87 | KDM4E (0.35) | POLBTSHRCHRM3ALDH1A1TRPM8 | |
| SCHEMBL4788452 | 0.86 | TSHR (0.36) | TSHRCHRM3ALDH1A1TRPM8TAAR1 | |
| SCHEMBL4787715 | 0.85 | CYP1A2 (0.38) | TSHRCHRM3ALDH1A1TRPM8TAAR1 | |
| SCHEMBL4789923 | 0.85 | CHRM3 (0.39) | TSHRCHRM3ALDH1A1TRPM8TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |