Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 4/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788059 | 0.94 | CHRM3 (0.37) | CHRM3ALDH1A1TSHRTRPM8TAAR1 | |
| SCHEMBL4789357 | 0.91 | POLB (0.35) | CHRM3ALDH1A1TSHRTRPM8TAAR1 | |
| SCHEMBL4789383 | 0.87 | CHRM3 (0.36) | CHRM3ALDH1A1TSHRTRPM8TAAR1 | |
| SCHEMBL4788452 | 0.86 | TSHR (0.36) | CHRM3ALDH1A1TSHRACHETRPM8 | |
| SCHEMBL4789923 | 0.85 | CHRM3 (0.39) | CTSLCHRM3ALDH1A1TSHRTRPM8 | |
| SCHEMBL4787715 | 0.85 | CYP1A2 (0.38) | CTSLCHRM3ALDH1A1TSHRTRPM8 | |
| SCHEMBL4790238 | 0.85 | ALDH1A1 (0.35) | CTSLCHRM3ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL4788471 | 0.83 | CHRM3 (0.37) | CHRM3ALDH1A1TSHRTRPM8TAAR1 | |
| SCHEMBL4789177 | 0.82 | CCR3 (0.33) | ALDH1A1TSHRTRPM8TAAR1HTR2A | |
| SCHEMBL4789676 | 0.82 | POLB (0.32) | CTSLALDH1A1TSHRTRPM8TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |