Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789834 | 0.89 | TRPM8 (0.39) | TRPM8ALDH1A1HTTKDM4ESIRT2 | |
| SCHEMBL4789846 | 0.89 | TRPM8 (0.39) | TRPM8ALDH1A1HTTKDM4ESIRT2 | |
| SCHEMBL4790480 | 0.85 | TRPM8 (0.41) | TRPM8CYP1A2CYP3A4ALDH1A1HTT | |
| SCHEMBL4787715 | 0.84 | CYP1A2 (0.38) | TRPM8CYP1A2CYP3A4MAPTALDH1A1 | |
| SCHEMBL4788453 | 0.80 | KDM4E (0.36) | TRPM8CYP1A2CYP3A4MAPTALDH1A1 | |
| SCHEMBL4790212 | 0.78 | MAPT (0.36) | TRPM8CYP1A2CYP3A4MAPTALDH1A1 | |
| SCHEMBL4789858 | 0.77 | ADRA1A (0.47) | TRPM8ALDH1A1KDM4ESIRT2SIRT1 | |
| SCHEMBL4790066 | 0.76 | KDM4E (0.35) | TRPM8CYP1A2CYP3A4MAPTALDH1A1 | |
| SCHEMBL4789932 | 0.74 | TRPM8 (0.39) | TRPM8ALDH1A1HTTKDM4ESIRT2 | |
| SCHEMBL4788059 | 0.73 | CHRM3 (0.37) | TRPM8ALDH1A1HPGDLMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |