Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789846 | 0.89 | TRPM8 (0.39) | TRPM8CHRM3ALDH1A1HTTKDM4E | |
| SCHEMBL4789932 | 0.88 | TRPM8 (0.39) | TRPM8ACHEALDH1A1HTTKDM4E | |
| SCHEMBL4789834 | 0.87 | TRPM8 (0.39) | TRPM8ACHEALDH1A1HTTKDM4E | |
| SCHEMBL4789935 | 0.85 | TRPM8 (0.38) | TRPM8ALDH1A1HTTKDM4ESIRT2 | |
| SCHEMBL4788471 | 0.82 | CHRM3 (0.37) | TRPM8CHRM3ALDH1A1TSHRTAAR1 | |
| SCHEMBL4789858 | 0.81 | ADRA1A (0.47) | TRPM8CHRM3ALDH1A1KDM4ESIRT2 | |
| SCHEMBL4788351 | 0.79 | ALDH1A1 (0.34) | TRPM8CHRM3ACHEALDH1A1TSHR | |
| SCHEMBL4789873 | 0.78 | CHRM3 (0.39) | TRPM8CHRM3ACHEALDH1A1KDM4E | |
| SCHEMBL4788458 | 0.78 | CHRM3 (0.38) | TRPM8CHRM3ACHEALDH1A1KDM4E | |
| SCHEMBL4789010 | 0.76 | ALDH1A1 (0.35) | TRPM8CHRM3ACHEALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | claimed |
| WO-2008117229-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-02 | — | — | WO | disclosed |