SCHEMBL4789995

SCHEMBL4789995

Nc1c(S(=O)(=O)O)cc(-c2cc(S(=O)(=O)O)c(N)c3c2C(=O)c2ccccc2C3=O)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNG2 P59768 5/20 0.62
GNB1 P62873 5/20 0.62
PGAM1 P18669 1/20 0.57
P2RY4 P51582 4/20 0.56
CYP1A2 P05177 3/20 0.55
PHLPP2 Q6ZVD8 2/20 0.55
CYP2C9 P11712 2/20 0.55
ALOX15 P16050 2/20 0.55
HSD17B10 Q99714 2/20 0.55
MAPK1 P28482 2/20 0.55
ALDH1A1 P00352 1/20 0.55
CYP3A4 P08684 1/20 0.55
HPGD P15428 1/20 0.55
CYP2C19 P33261 1/20 0.55
HIF1A Q16665 1/20 0.55
DAPK1 P53355 1/20 0.55
FTO Q9C0B1 1/20 0.51
GRK6 P43250 1/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8020165 0.95 GNG2 (0.58) GNG2GNB1PGAM1P2RY4CYP1A2
SCHEMBL13995665 0.92 GNG2 (0.56) GNG2GNB1PGAM1P2RY4CYP1A2
SCHEMBL11307767 0.90 GNG2 (0.62) GNG2GNB1PGAM1P2RY4CYP1A2
SCHEMBL3363864 0.88 GNG2 (0.60) GNG2GNB1PGAM1P2RY4CYP1A2
SCHEMBL29506785 0.88 GNG2 (0.60) GNG2GNB1PGAM1P2RY4CYP1A2
SCHEMBL15259673 0.87 P2RY4 (0.53) GNG2GNB1PGAM1P2RY4CYP1A2
Hydrochloric Acid SCHEMBL11764888 0.87 GNG2 (0.59) GNG2GNB1PGAM1P2RY4CYP1A2
SCHEMBL28420647 0.87 GNG2 (0.59) GNG2GNB1PGAM1P2RY4CYP1A2
SCHEMBL7822355 0.87 GNG2 (0.59) GNG2GNB1PGAM1P2RY4CYP1A2
SCHEMBL8007945 0.87 GNG2 (0.53) GNG2GNB1PGAM1P2RY4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10338832-A None JP disclosed
EP-1830957-B1 EPOXIDATION PROCESS WHEREIN THE TITANIUM OR VANADIUM ZEOLITE CATALYST IS PRETEATED WITH AN AMINO POLYACID LYONDELL CHEMICAL TECH LP (US) 2008-11-12 EP disclosed
EP-1830957-A1 EPOXIDATION PROCESS WHEREIN THE TITANIUM OR VANADIUM ZEOLITE CATALYST IS PRETEATED WITH AN AMINO POLYACID Lyondell Chemical Technology, L.P. (US) 2007-09-12 EP disclosed
WO-2006065311-A1 EPOXIDATION PROCESS WHEREIN THE TITANIIUM OR VANADIUM ZEOLITE CATALYST IS PRETREATED WITH AN AMINO POLYACID LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) 2006-06-22 WO disclosed
US-20060135795-A1 reacting olefin with hydrogen peroxide in presence of titanium or vanadium zeolite which is pretreated with ethylenediaminetetraacetic acid LYONDELL CHEMICAL TECHNOLOGY, L.P. 2006-06-22 US disclosed
US-7057056-B1 Epoxidation catalyst LYONDELL CHEMICAL TECHNOLOGY, L.P. (US) 2006-06-06 US disclosed
JP-2000019725-A RED-COLORED RESIST INK NIPPON STEEL CHEM CO LTD 2000-01-21 JP disclosed
JP-H10338832-A RED COLOR RESIST INK NIPPON STEEL CHEM CO LTD 1998-12-22 JP disclosed