SCHEMBL13995665

SCHEMBL13995665

CS(=O)(=O)c1cc(-c2cc(S(=O)(=O)O)c(N)c3c2C(=O)c2ccccc2C3=O)c2c(c1N)C(=O)c1ccccc1C2=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNG2 P59768 5/20 0.56
GNB1 P62873 5/20 0.56
PHLPP2 Q6ZVD8 2/20 0.53
P2RY4 P51582 5/20 0.51
CYP1A2 P05177 3/20 0.50
CYP2C9 P11712 2/20 0.50
ALOX15 P16050 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MAPK1 P28482 2/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
CYP2C19 P33261 1/20 0.50
HIF1A Q16665 1/20 0.50
PGAM1 P18669 1/20 0.50
DAPK1 P53355 1/20 0.49
FTO Q9C0B1 1/20 0.46
CYP1A1 P04798 1/20 0.43
GRK6 P43250 1/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4789995 0.92 GNG2 (0.62) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL8020165 0.88 GNG2 (0.58) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL15259673 0.83 P2RY4 (0.53) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL11307767 0.83 GNG2 (0.62) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL13286975 0.82 GNG2 (0.59) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL10807942 0.81 MEN1 (0.54) GNG2GNB1P2RY4CYP1A2MAPK1
SCHEMBL3363864 0.81 GNG2 (0.60) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL29506785 0.81 GNG2 (0.60) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL8029074 0.81 GNG2 (0.52) GNG2GNB1PHLPP2P2RY4CYP1A2
SCHEMBL28436123 0.81 GNG2 (0.52) GNG2GNB1PHLPP2P2RY4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080319089-A1 Method of colouring carrier materials MULLER MARTIN 2008-12-25 US disclosed
US-20070051275-A1 Method of colouring carrier materials CIBA SPECIALTY CHEMICALS CORP. 2007-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319089-A1 Method of colouring carrier materials CRYAA, SLC67A1, SOD3 GNG2 498/4885GNB1 760/4885PHLPP2 2819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.