SCHEMBL7822355

SCHEMBL7822355

Nc1c(S(=O)(=O)O)cc(O)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNG2 P59768 5/20 0.59
GNB1 P62873 5/20 0.59
DAPK1 P53355 2/20 0.56
HPGD P15428 3/20 0.56
ALOX15 P16050 3/20 0.56
HSD17B10 Q99714 3/20 0.56
ALDH1A1 P00352 3/20 0.56
MAPK1 P28482 3/20 0.56
PHLPP2 Q6ZVD8 2/20 0.56
CYP3A4 P08684 2/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C9 P11712 2/20 0.56
CYP2C19 P33261 1/20 0.56
HIF1A Q16665 1/20 0.56
P2RY4 P51582 3/20 0.54
PGAM1 P18669 1/20 0.54
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
MAPT P10636 3/20 0.53
TDP1 Q9NUW8 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11093274 0.98 GNG2 (0.58) GNG2GNB1DAPK1HPGDALOX15
SCHEMBL11307767 0.87 GNG2 (0.62) GNG2GNB1DAPK1HPGDALOX15
SCHEMBL4789995 0.87 GNG2 (0.62) GNG2GNB1DAPK1HPGDALOX15
SCHEMBL29337571 0.86 NQO1 (0.50) GNG2GNB1DAPK1HPGDALOX15
SCHEMBL29506785 0.85 GNG2 (0.60) GNG2GNB1DAPK1HPGDALOX15
SCHEMBL3363864 0.85 GNG2 (0.60) GNG2GNB1DAPK1HPGDALOX15
SCHEMBL11093270 0.84 FTO (0.69) P2RY4MEN1KMT2ATTRPOLB
SCHEMBL28420647 0.84 GNG2 (0.59) GNG2GNB1DAPK1HPGDALOX15
Hydrochloric Acid SCHEMBL11764888 0.84 GNG2 (0.59) GNG2GNB1DAPK1HPGDALOX15
SCHEMBL29394271 0.83 PGAM1 (0.66) DAPK1HPGDALOX15HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 US disclosed
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION L'OREAL (FR) 2023-08-03 US disclosed
CN-113105369-A Sulfonation method for preparing bromamine acid by solvent method 林齐坤 2021-07-13 CN disclosed
JP-2001115055-A ANTHRAQUINONE-BASED DYE COMPOSITION AND ITS PRODUCTION SUMITOMO CHEM CO LTD 2001-04-24 JP disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
US-4521341-A Process for the preparation of 1,4-diamino-anthraquinone-2-sulphonic acid BAYER AKTIENGESELLSCHAFT (DE) 1985-06-04 US disclosed
US-4422973-A Process for the preparation of 1,4-diamino-2,3-dicyano-anthraquinone BAYER AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed
EP-0051783-B1 PROCESS FOR PREPARING 1,4-DIAMINO-ANTHRAQUINONE-2-SULPHONIC ACID BAYER AG (DE) 1983-11-16 EP disclosed
EP-0034257-B1 PROCESS FOR THE PREPARATION OF 1,4-DIAMINO-2,3-DICYANO-ANTHRAQUINONE BAYER AG (DE) 1983-01-26 EP disclosed
EP-0034257-A2 Process for the preparation of 1,4-diamino-2,3-dicyano-anthraquinone BAYER AG (DE) 1981-08-26 EP disclosed
US-RE29577-E Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1978-03-14 US disclosed
US-4054586-A Process for preparing 1-aminoanthraquinone having high purity MITSUI TOATSU CHEMICALS INCORPORATED (JA) 1977-10-18 US disclosed
US-4036862-A FOR POLYESTERS BAYER AKTIENGESELLSCHAFT (DT) 1977-07-19 US disclosed
US-4035398-A Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-07-12 US disclosed
US-4017524-A PRINTING AND DYEING OF SYNTHETIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1977-04-12 US disclosed
US-4008222-A POLYESTERS BAYER AKTIENGESELLSCHAFT (DT) 1977-02-15 US disclosed
US-3963763-A Anthraquinone dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1976-06-15 US disclosed
US-3959315-A SULFONAMIDO BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed
US-3957822-A POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240954-A1 USE OF ANTHRAQUINONE DYES AND OF FLUORESCENT DYES FOR DYEING KERATIN FIBRES, DYEING PROCESS AND COMPOSITION KRT18, CUTA, KLK5 GNG2 2341/4885GNB1 2037/4885DAPK1 1158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.