SCHEMBL4790318

SCHEMBL4790318

O=C(C=Cc1ccccc1)C(O)C(O)CO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
LMNA P02545 3/20 0.50
ALDH1A1 P00352 2/20 0.50
HDAC3 O15379 2/20 0.50
HDAC4 P56524 2/20 0.50
HDAC1 Q13547 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
PLIN1 O60240 2/20 0.50
RECQL P46063 2/20 0.50
PLIN5 Q00G26 2/20 0.50
ABHD5 Q8WTS1 2/20 0.50
F3 P13726 2/20 0.50
TNKS O95271 1/20 0.50
HCAR2 Q8TDS4 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
TNKS2 Q9H2K2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27534782 0.89 LMNA (0.46) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL30864651 0.85 MMP2 (0.59) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL3133036 0.85 MMP2 (0.59) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL7665404 0.82 MAPT (0.53) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL29964902 0.82 MAPT (0.57) MAPTLMNAALDH1A1HDAC3HDAC4
SCHEMBL30486016 0.81 GSK3B (0.59) LMNAHDAC3HDAC4HDAC1HDAC2
Dimethylformamide SCHEMBL27538857 0.80 NPC1 (0.40) MAPTLMNAALDH1A1HDAC3HDAC4
Mannitol SCHEMBL28730590 0.79 LMNA (0.66) MAPTLMNAALDH1A1HDAC3HDAC4
Cinnamic Acid SCHEMBL28748113 0.79 HCAR2 (0.66) MAPTLMNAALDH1A1HDAC3HDAC4
Cinnamic Acid SCHEMBL15004793 0.79 HCAR2 (0.70) MAPTLMNAALDH1A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827583-B2 Vegetable oil-based material as a substitute for carnauba wax IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2023-11-28 US disclosed
US-20220220066-A1 NOVEL VEGETABLE OIL-BASED MATERIAL AS A SUBSTITUTE FOR CARNAUBA WAX UNIV IOWA STATE RES FOUND INC (US) 2022-07-14 US disclosed
US-11319281-B2 Vegetable oil-based material as a substitute for carnauba wax IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2022-05-03 US disclosed
US-20210047264-A1 VEGETABLE OIL-BASED MATERIAL AS A SUBSTITUTE FOR CARNAUBA WAX IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2021-02-18 US disclosed
US-10851046-B2 Vegetable oil-based material as a substitute for carnauba wax IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2020-12-01 US disclosed
US-20180297937-A1 NOVEL VEGETABLE OIL-BASED MATERIAL AS A SUBSTITUTE FOR CARNAUBA WAX IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2018-10-18 US disclosed
JP-2008156255-A ANTIOXIDANT OSAKA PREFECTURE UNIV 2008-07-10 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11827583-B2 Vegetable oil-based material as a substitute for carnauba wax FASN, C5, ACSL1 MAPT 1958/4885LMNA 1366/4885ALDH1A1 1122/4885
US-20180297937-A1 NOVEL VEGETABLE OIL-BASED MATERIAL AS A SUBSTITUTE FOR CARNAUBA WAX FASN, ACSL1, C5 MAPT 2405/4885LMNA 1705/4885ALDH1A1 1002/4885
US-10851046-B2 Vegetable oil-based material as a substitute for carnauba wax FASN, C5, ACSL1 MAPT 1958/4885LMNA 1366/4885ALDH1A1 1122/4885
US-20220220066-A1 NOVEL VEGETABLE OIL-BASED MATERIAL AS A SUBSTITUTE FOR CARNAUBA WAX FASN, ACSL1, C5 MAPT 2405/4885LMNA 1705/4885ALDH1A1 1002/4885
US-20210047264-A1 VEGETABLE OIL-BASED MATERIAL AS A SUBSTITUTE FOR CARNAUBA WAX FASN, C5, ACSL1 MAPT 1958/4885LMNA 1366/4885ALDH1A1 1122/4885
US-11319281-B2 Vegetable oil-based material as a substitute for carnauba wax FASN, C5, ACSL1 MAPT 1958/4885LMNA 1366/4885ALDH1A1 1122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.