Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.59 |
| ▸ | F3 | P13726 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133036 | 0.83 | MMP2 (0.59) | GSK3BF3HDAC3HDAC1HDAC2 | |
| SCHEMBL30864651 | 0.83 | MMP2 (0.59) | GSK3BF3HDAC3HDAC1HDAC2 | |
| 4-Methoxycinnamic Acid SCHEMBL28334458 | 0.82 | THRB (0.76) | GSK3BF3THRBATMLMNA | |
| SCHEMBL30791440 | 0.81 | MMP9 (0.63) | GSK3BF3THRBLMNATDP1 | |
| SCHEMBL2266493 | 0.81 | MMP9 (0.63) | GSK3BF3THRBLMNATDP1 | |
| SCHEMBL4790318 | 0.81 | MAPT (0.50) | F3LMNATDP1HDAC3HDAC1 | |
| SCHEMBL21356927 | 0.79 | F3 (0.68) | GSK3BF3THRBATMLMNA | |
| SCHEMBL21356925 | 0.79 | F3 (0.68) | GSK3BF3THRBATMLMNA | |
| SCHEMBL10843269 | 0.79 | F3 (0.68) | GSK3BF3THRBATMLMNA | |
| SCHEMBL10843273 | 0.79 | F3 (0.68) | GSK3BF3THRBATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210755-A1 | FUNCTIONAL SKIN COATING POLYMER | THE JOHNS HOPKINS UNIVERSITY | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210755-A1 | FUNCTIONAL SKIN COATING POLYMER | CUTA, PUF60, SUN2 | GSK3B 4093/4885F3 502/4885THRB 4599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.