Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1493987 | 1.00 | KDM4E (0.34) | KDM4ERAB9A | |
| SCHEMBL1493990 | 1.00 | KDM4E (0.34) | KDM4ERAB9A | |
| SCHEMBL4792185 | 1.00 | KDM4E (0.34) | KDM4ERAB9A | |
| SCHEMBL5532557 | 0.86 | RAB9A (0.31) | KDM4ERAB9A | |
| SCHEMBL15255989 | 0.85 | RAB9A (0.30) | KDM4ERAB9A | |
| SCHEMBL18430743 | 0.73 | POLB (0.46) | KDM4ERAB9A | |
| SCHEMBL1494014 | 0.73 | BRPF1 (0.31) | — | |
| SCHEMBL1493953 | 0.65 | LMNA (0.44) | — | |
| SCHEMBL1494392 | 0.65 | MAPT (0.40) | RAB9A | |
| SCHEMBL27676316 | 0.63 | MAP3K5 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924264-A1 | DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025925-A1 | DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | disclosed |