Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022724 | 0.85 | HDAC3 (0.44) | MAPTHDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL16758640 | 0.85 | NPC1 (0.46) | MAPTHDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL11022744 | 0.83 | MAPT (0.41) | MAPTHDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL9757149 | 0.80 | MAPT (0.47) | MAPTHDAC4ALDH1A1LMNANPC1 | |
| SCHEMBL10480315 | 0.79 | MAPT (0.46) | MAPTHDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL2123396 | 0.79 | MAPT (0.50) | MAPTHDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL11821238 | 0.79 | RAB9A (0.44) | MAPTHDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL11800389 | 0.79 | RAB9A (0.42) | MAPTHDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL2147325 | 0.78 | MAPT (0.48) | MAPTHDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL86097 | 0.78 | MAPT (0.48) | MAPTHDAC4GAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304918-A | Process for preparing benzoxazolyl propionic acid derivatives | RAVIZZA S.P.A. (IT) | 1981-12-08 | — | — | US | claimed |
| JP-54098798-A | — | — | None | — | — | JP | disclosed |
| US-20080287434-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | SANOFI-AVENTIS (FR) | 2008-11-20 | — | — | US | disclosed |
| EP-1931620-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIQUIDS | Sanofi-Aventis (FR) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007034252-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIQUIDS | SANOFI-AVENTIS (FR) | 2007-03-29 | — | — | WO | disclosed |
| US-4943645-A | Benzoquinone derivatives and production thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4874752-A | INHIBIT COLLAGEN BIOSYNTHESIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-17 | — | — | US | disclosed |
| US-4808339-A | ARTHRITIS, ASTHMA, CIRRHOSIS, RHINITIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| US-4751303-A | INHIBIT COLLAGEN BIOSYNTHESIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-06-14 | — | — | US | disclosed |
| EP-0092136-B1 | BENZOQUINONE DERIVATIVES AND PRODUCTION THEREOF | Takeda Chemical Industries, Ltd. (JP) | 1985-08-28 | — | — | EP | disclosed |
| US-4526719-A | Benzoquinone derivatives and production thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| EP-0092136-A1 | Benzoquinone derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1983-10-26 | — | — | EP | disclosed |
| US-4304918-A | Process for preparing benzoxazolyl propionic acid derivatives | RAVIZZA S.P.A. (IT) | 1981-12-08 | — | — | US | disclosed |
| US-4304918-A | Process for preparing benzoxazolyl propionic acid derivatives | RAVIZZA S.P.A. (IT) | 1981-12-08 | — | — | US | disclosed |
| US-4304918-A | Process for preparing benzoxazolyl propionic acid derivatives | RAVIZZA S.P.A. (IT) | 1981-12-08 | — | — | US | disclosed |
| JP-S5498798-A | OXAZOLO(I,J)QUINOLINE DERIVATIVE | NIPPON NOHYAKU CO LTD | 1979-08-03 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287434-A1 | New amino-alkyl-amide derivatives as CCR3 receptor ligands | CCR3, CCR1, CCR4 | MAPT 4311/4885HDAC4 1869/4885HDAC3 455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.