Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5305682 | 0.83 | GRIK1 (0.49) | GRIK1DRD2FLT3NPC1RAB9A | |
| SCHEMBL13134189 | 0.81 | GRIK1 (0.48) | GRIK1DRD2FLT3NPC1RAB9A | |
| SCHEMBL31487774 | 0.79 | MTNR1A (0.53) | GRIK1DRD2FLT3NPC1RAB9A | |
| SCHEMBL4413986 | 0.79 | MTNR1A (0.53) | GRIK1DRD2FLT3NPC1RAB9A | |
| SCHEMBL9269321 | 0.77 | GRIK1 (0.56) | GRIK1DRD2FLT3NPC1RAB9A | |
| SCHEMBL4195099 | 0.76 | NPC1 (0.49) | GRIK1DRD2FLT3NPC1RAB9A | |
| SCHEMBL29493370 | 0.76 | NPC1 (0.49) | GRIK1DRD2FLT3NPC1RAB9A | |
| SCHEMBL5515054 | 0.76 | GRIK1 (0.51) | GRIK1DRD2FLT3NPC1RAB9A | |
| SCHEMBL5493171 | 0.76 | KDM4E (0.51) | GRIK1DRD2FLT3NPC1RAB9A | |
| SCHEMBL4410319 | 0.75 | DRD2 (0.49) | GRIK1DRD2FLT3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973902-A2 | 3-HETEROCYCLYLACRYLAMIDE COMPOUNDS AS FABI INHIBITORS AND ANTIBACTERIAL AGENTS | Affinium Pharmaceuticals, Inc. (CA) | 2008-10-01 | — | — | EP | claimed |
| WO-2007067416-A2 | HETEROCYCLYLACRYLAMIDE COMPOUNDS AS FABI INHIBITORS AND ANTIBACTERIAL AGENTS | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2007-06-14 | — | — | WO | claimed |