SCHEMBL479437

SCHEMBL479437

COCCOCCOCCOc1cc(Br)sc1Br

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
L3MBTL1 Q9Y468 9/20 0.37
MAPT P10636 4/20 0.37
TDP1 Q9NUW8 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 1/20 0.35
KDM4E B2RXH2 2/20 0.34
CHEK1 O14757 1/20 0.34
SLC6A4 P31645 1/20 0.33
F2RL3 Q96RI0 1/20 0.33
POLB P06746 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
AR P10275 1/20 0.32
NPC1 O15118 1/20 0.32
RECQL P46063 1/20 0.31
KDM1A O60341 1/20 0.31
NCF1 P14598 1/20 0.31
PLAU P00749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15412839 1.00 ALDH1A1 (0.39) ALDH1A1L3MBTL1MAPTTDP1SMN1; SMN2
SCHEMBL5573800 1.00 ALDH1A1 (0.39) ALDH1A1L3MBTL1MAPTTDP1SMN1; SMN2
SCHEMBL31247939 0.86 ALDH1A1 (0.39) ALDH1A1L3MBTL1MAPTTDP1SMN1; SMN2
SCHEMBL13876373 0.86 NCF1 (0.36) ALDH1A1L3MBTL1MAPTTDP1SMN1; SMN2
SCHEMBL19910770 0.84 MAPT (0.40) L3MBTL1MAPTTDP1SMN1; SMN2LMNA
SCHEMBL14854547 0.83 RARB (0.38) ALDH1A1L3MBTL1MAPTTDP1SMN1; SMN2
SCHEMBL1403969 0.76 L3MBTL1 (0.34) ALDH1A1L3MBTL1MAPTTDP1SMN1; SMN2
SCHEMBL2342975 0.76 F2 (0.31) L3MBTL1MAPT
SCHEMBL15412774 0.76 F2 (0.31) L3MBTL1MAPT
SCHEMBL14870995 0.76 L3MBTL1 (0.51) ALDH1A1L3MBTL1MAPTTDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9224540-B2 Conductive polymer for solid electrolyte capacitor SOLVAY USA, INC. (US) 2015-12-29 US disclosed
EP-2855486-A1 SPIRO TETRAHYDRO - BENZOTHIOPHEN DERIVATIVES USEFUL FOR THE TREATMENT NEURODEGENERATIVE DISEASES Ares Trading SA (CH) 2015-04-08 EP disclosed
EP-2855554-A2 CONDUCTIVE POLYMER FOR SOLID ELECTROLYTIC CAPACITOR Solvay USA Inc. (US) 2015-04-08 EP disclosed
US-20140014881-A1 CONDUCTIVE POLYMER FOR SOLID ELECTROLYTE CAPACITOR PLEXTRONICS, INC. (US) 2014-01-16 US disclosed
WO-2013178322-A1 SPIRO TETRAHYDRO - BENZOTHIOPHEN DERIVATIVES USEFUL FOR THE TREATMENT NEURODEGENERATIVE DISEASES ARES TRADING S.A. (CH) 2013-12-05 WO disclosed
WO-2013181165-A2 CONDUCTIVE POLYMER FOR SOLID ELECTROLYTIC CAPACITOR PLEXTRONICS, INC. (US) 2013-12-05 WO disclosed
US-20120119154-A1 Electroconductive Coating Composition And Process For Production Of Electroconductive Coating Film SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2012-05-17 US disclosed
EP-2412770-A1 ELECTROCONDUCTIVE COATING COMPOSITION AND PROCESS FOR PRODUCTION OF ELECTROCONDUCTIVE COATING FILM Sanyo Chemical Industries, Ltd. (JP) 2012-02-01 EP disclosed