Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CPN1 | P15169 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4799849 | 0.85 | ESR1 (0.51) | ESR1ESR2LMNASLC7A5ALDH1A1 | |
| SCHEMBL27658935 | 0.85 | ESR1 (0.48) | ESR1ESR2SRCLMNAHSD17B10 | |
| SCHEMBL76635 | 0.83 | CYP2C19 (0.57) | SRCLMNAHSD17B10ALDH1A1CYP2C19 | |
| SCHEMBL9702510 | 0.83 | ESR1 (0.50) | ESR1ESR2SRCLMNAHSD17B10 | |
| SCHEMBL12073123 | 0.82 | PTPN1 (0.44) | PTPN1L3MBTL1ALDH1A1GAACYP2C19 | |
| SCHEMBL7087165 | 0.81 | ESR1 (0.48) | ESR1ESR2SRCLMNAHSD17B10 | |
| SCHEMBL11248515 | 0.79 | PTGS1 (0.61) | ESR1ESR2SRCLMNAHSD17B10 | |
| SCHEMBL6461974 | 0.79 | L3MBTL1 (0.62) | ESR1ESR2SRCLMNAHSD17B10 | |
| SCHEMBL1118743 | 0.79 | TAAR1 (0.52) | ESR1ESR2SRCLMNAHSD17B10 | |
| SCHEMBL5488862 | 0.79 | ESR1 (0.47) | ESR1ESR2SRCLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999095-A2 | PROCESSES FOR CONVERSION OF TYROSINE TO P-HYDROXYSTYRENE AND P-ACETOXYSTYRENE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-12-10 | — | — | EP | claimed |
| US-7402713-B2 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-22 | — | — | US | claimed |
| WO-2007103478-A2 | PROCESSES FOR CONVERSION OF TYROSINE TO P-HYDROXYSTYRENE AND P-ACETOXYSTYRENE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-09-13 | — | — | WO | claimed |
| US-20070213569-A1 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-09-13 | — | — | US | claimed |
| CN-113402490-B | Preparation method of 1,2,6, 7-tetrahydro-8H-indeno [5,4-b ] furan-8-one | 白银京宇新药业有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-113402490-A | Preparation method of 1,2,6, 7-tetrahydro-8H-indeno [5,4-b ] furan-8-one | 白银京宇新药业有限公司 | 2021-09-17 | — | — | CN | disclosed |
| CN-101400634-A | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | DU PONT (US) | 2009-04-01 | — | — | CN | disclosed |
| EP-1999095-A2 | PROCESSES FOR CONVERSION OF TYROSINE TO P-HYDROXYSTYRENE AND P-ACETOXYSTYRENE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-12-10 | — | — | EP | disclosed |
| US-7402713-B2 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-22 | — | — | US | disclosed |
| US-7402713-B2 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-22 | — | — | US | disclosed |
| US-7402713-B2 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-22 | — | — | US | disclosed |
| WO-2007103478-A2 | PROCESSES FOR CONVERSION OF TYROSINE TO P-HYDROXYSTYRENE AND P-ACETOXYSTYRENE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-09-13 | — | — | WO | disclosed |
| WO-2007103478-A2 | PROCESSES FOR CONVERSION OF TYROSINE TO P-HYDROXYSTYRENE AND P-ACETOXYSTYRENE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-09-13 | — | — | WO | disclosed |
| US-20070213569-A1 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-09-13 | — | — | US | disclosed |
| US-20070213569-A1 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-09-13 | — | — | US | disclosed |
| US-20070213569-A1 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213569-A1 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | TH, PAH, TPST2 | ESR1 4045/4885ESR2 3498/4885SRC 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.