SCHEMBL5488862

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9702510	0.83	ESR1 (0.50)	ESR1ESR2SRCLMNAHSD17B10
	SCHEMBL1922327	0.83	CYP2C19 (0.57)	SRCLMNAHSD17B10ALDH1A1CYP2C19
	SCHEMBL7087165	0.81	ESR1 (0.48)	ESR1ESR2SRCLMNAHSD17B10
	SCHEMBL1118667	0.79	TAAR1 (0.52)	ESR1ESR2SRCLMNAHSD17B10
	SCHEMBL4795362	0.79	ESR1 (0.47)	ESR1ESR2SRCLMNAHSD17B10
	SCHEMBL819392	0.79	LMNA (0.61)	ESR1ESR2SRCLMNAHSD17B10
	SCHEMBL1118743	0.79	TAAR1 (0.52)	ESR1ESR2SRCLMNAHSD17B10
	SCHEMBL11248515	0.79	PTGS1 (0.61)	ESR1ESR2SRCLMNAHSD17B10
	SCHEMBL6461974	0.79	L3MBTL1 (0.62)	ESR1ESR2SRCLMNAHSD17B10
	SCHEMBL7040363	0.79	ESR1 (0.47)	ESR1ESR2SRCLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.