Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 7/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 7/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 7/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 7/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 7/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 7/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 7/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2045109 | 0.75 | HSD17B10 (0.43) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL17417709 | 0.68 | GPR17 (0.46) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL17417782 | 0.68 | F7 (0.50) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL17417717 | 0.68 | MYC (0.46) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL17417708 | 0.66 | TUBB1 (0.46) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL35210895 | 0.65 | GPR17 (0.46) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL2769281 | 0.64 | CYP2A6 (0.53) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL25331893 | 0.64 | PRKAG1 (0.50) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL22790098 | 0.63 | PRKAB2 (0.51) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL6838151 | 0.62 | CYP1A2 (0.49) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120079-A3 | 4-AMINOMETHYL-6-BROMINE-5-HYDROXYINDOL-3-CARBOXILATE DERIVATIVES, METHOD FOR THE PRODUCTION (VARIANTS) AND THE USE THEREOF | OBSCHESTVO S OGRANICHENNOY OTV (RU) | 2008-01-10 | — | — | WO | disclosed |
| WO-2007120079-A2 | 4-AMINOMETHYL-6-BROMINE-5-HYDROXYINDOL-3-CARBOXILATE DERIVATIVES, METHOD FOR THE PRODUCTION (VARIANTS) AND THE USE THEREOF | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOSTJU 'MBF' (RU) | 2007-10-25 | — | — | WO | disclosed |