Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4796480 | 1.00 | ALDH1A1 (0.49) | ALDH1A1HSD17B10LMNAL3MBTL1POLB | |
| SCHEMBL4803342 | 0.84 | L3MBTL1 (0.40) | ALDH1A1HSD17B10LMNAL3MBTL1POLB | |
| SCHEMBL4803335 | 0.84 | L3MBTL1 (0.40) | ALDH1A1HSD17B10LMNAL3MBTL1POLB | |
| SCHEMBL15564386 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HSD17B10LMNAL3MBTL1POLB | |
| SCHEMBL18980750 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HSD17B10LMNAL3MBTL1POLB | |
| SCHEMBL7453248 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HSD17B10LMNAL3MBTL1POLB | |
| SCHEMBL25177942 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HSD17B10LMNAL3MBTL1POLB | |
| SCHEMBL7438640 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HSD17B10LMNAL3MBTL1POLB | |
| SCHEMBL4804598 | 0.79 | EPHX2 (0.35) | ALDH1A1HSD17B10LMNAL3MBTL1POLB | |
| SCHEMBL4804601 | 0.79 | EPHX2 (0.35) | ALDH1A1HSD17B10LMNAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7326794-B2 | Process for the preparation of high purity perindopril and intermediates useful in the synthesis | LES LABORATOIRES SERVIER (FR) | 2008-02-05 | — | — | US | disclosed |
| US-7279595-B2 | Process for the preparation of high purity perindopril | LES LABORATOIRES SERVIER (FR) | 2007-10-09 | — | — | US | disclosed |
| US-20070197821-A1 | Process for the preparation of high purity perindopril | LES LABORATOIRES SERVIER (FR) | 2007-08-23 | — | — | US | disclosed |
| EP-1333026-B1 | Process for the preparation of high purity perindopril and intermediates useful in the synthesis | SERVIER LAB (FR) | 2007-06-27 | — | — | EP | disclosed |
| US-20050119492-A1 | Process for the preparation of high purity perindopril and intermediates useful in the synthesis | LES LABORATOIRES SERVIER (FR) | 2005-06-02 | — | — | US | disclosed |
| WO-2003064388-A2 | PROCESS FOR THE PREPARATION OF HIGH PURITY PERINDOPRIL AND INTERMEDIATES USEFUL IN THE SYNTHESIS | LES LABORATOIRES SERVIER (FR) | 2003-08-07 | — | — | WO | disclosed |
| EP-1333026-A1 | Process for the preparation of high purity perindopril and intermediates useful in the synthesis | Les Laboratoires Servier (FR) | 2003-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197821-A1 | Process for the preparation of high purity perindopril | ACE, AGTR1, ACE2 | ALDH1A1 142/4885HSD17B10 1425/4885LMNA 1116/4885 |
| US-20050119492-A1 | Process for the preparation of high purity perindopril and intermediates useful in the synthesis | ACE, AGTR1, ACE2 | ALDH1A1 150/4885HSD17B10 1068/4885LMNA 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.