Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 5/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TPO | P07202 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 3/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795580 | 0.84 | MEN1 (0.36) | DHFRCYP3A4DPP4DPP8DPP9 | |
| SCHEMBL4794363 | 0.82 | ALDH1A1 (0.37) | SMN1; SMN2 | |
| SCHEMBL4759492 | 0.78 | MCHR1 (0.33) | KCNH2 | |
| SCHEMBL4796924 | 0.72 | MEN1 (0.34) | SMN1; SMN2 | |
| SCHEMBL4790457 | 0.61 | TLR8 (0.38) | MPOKCNH2SMN1; SMN2 | |
| SCHEMBL25070257 | 0.57 | ALDH1A1 (0.40) | DHFR | |
| SCHEMBL17236140 | 0.56 | NOS2 (0.42) | MPO | |
| SCHEMBL18315118 | 0.55 | NOS2 (0.45) | — | |
| Hydrochloric Acid SCHEMBL17224997 | 0.55 | NOS2 (0.41) | MPO | |
| SCHEMBL4129260 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009076-A2 | SUBSTITUTED PYRIDO(3,2-D)PYRIMIDINES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-01-24 | — | — | WO | disclosed |