Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.59 |
| ▸ | CCR2 | P41597 | 17/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3038763 | 0.96 | TACR1 (0.58) | TACR1CCR2CYP3A4 | |
| SCHEMBL5728946 | 0.82 | CCR2 (0.50) | TACR1CCR2CYP3A4 | |
| SCHEMBL14221691 | 0.82 | TACR1 (0.65) | TACR1CCR2CYP3A4 | |
| SCHEMBL3029909 | 0.81 | TACR1 (0.59) | TACR1CCR2 | |
| SCHEMBL3029890 | 0.81 | CCR2 (0.51) | CCR2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL3036646 | 0.81 | TACR1 (0.64) | TACR1CCR2CYP3A4 | |
| SCHEMBL3038764 | 0.80 | CCR2 (0.48) | CCR2CYP3A4 | |
| SCHEMBL7919481 | 0.79 | ATM (0.53) | TACR1 | |
| SCHEMBL4731356 | 0.78 | TACR1 (0.44) | TACR1CCR2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL3030594 | 0.78 | TACR1 (0.64) | TACR1CCR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |