Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.64 |
| ▸ | CCR2 | P41597 | 12/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14221691 | 0.99 | TACR1 (0.65) | TACR1CCR2MTORCYP3A4ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3030594 | 0.94 | TACR1 (0.64) | TACR1CCR2MTORCYP3A4ALDH1A1 | |
| SCHEMBL3036649 | 0.81 | CCR2 (0.49) | TACR1CCR2MTORCYP3A4ALDH1A1 | |
| SCHEMBL4797150 | 0.81 | TACR1 (0.59) | TACR1CCR2CYP3A4 | |
| SCHEMBL4732010 | 0.80 | CCR2 (0.51) | TACR1CCR2MTORCYP3A4ALDH1A1 | |
| SCHEMBL13222832 | 0.79 | CYP2D6 (0.48) | TACR1CCR2MTORCYP3A4ALDH1A1 | |
| SCHEMBL5730547 | 0.79 | CCR2 (0.49) | TACR1CCR2MTORCYP3A4ALDH1A1 | |
| SCHEMBL3029909 | 0.78 | TACR1 (0.59) | TACR1CCR2MTOR | |
| SCHEMBL5729397 | 0.78 | TACR1 (0.47) | TACR1CCR2MTORCYP3A4ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3038763 | 0.77 | TACR1 (0.58) | TACR1CCR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | EPIX DELAWARE, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | CCR2, CCR1, CCR5 | TACR1 539/4885CCR2 1/4885MTOR 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.