Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4797195 | 1.00 | KMT2A (0.50) | KMT2AMEN1POLBSENP7CASP6 | |
| SCHEMBL4801364 | 0.92 | MAPT (0.50) | KMT2AMEN1POLBSENP7CASP6 | |
| SCHEMBL4801382 | 0.92 | MAPT (0.50) | KMT2AMEN1POLBSENP7CASP6 | |
| SCHEMBL4800748 | 0.78 | ALDH1A1 (0.50) | KMT2AMEN1POLBSENP7CASP6 | |
| SCHEMBL4800762 | 0.78 | ALDH1A1 (0.50) | KMT2AMEN1POLBSENP7CASP6 | |
| SCHEMBL4797873 | 0.78 | CCR2 (0.45) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4797886 | 0.78 | CCR2 (0.45) | GAAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4798939 | 0.76 | MAPT (0.46) | KMT2AMEN1POLBLMNAMAPT | |
| SCHEMBL4798224 | 0.73 | ALDH1A1 (0.54) | KMT2AMEN1POLBSENP7CASP6 | |
| SCHEMBL4800681 | 0.72 | ALDH1A1 (0.56) | KMT2AMEN1POLBSENP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342039-B2 | Substituted indole oximes | WYETH (US) | 2008-03-11 | — | — | US | claimed |
| US-20050119326-A1 | Substituted aryloximes | WYETH (US) | 2005-06-02 | — | — | US | claimed |
| US-7342039-B2 | Substituted indole oximes | WYETH (US) | 2008-03-11 | — | — | US | disclosed |
| US-20050119326-A1 | Substituted aryloximes | WYETH (US) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119326-A1 | Substituted aryloximes | IDO2, TDO2, IDO1 | KMT2A 382/4885MEN1 3902/4885POLB 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.