Sulfuric Acid

Sulfuric Acid

SCHEMBL479725

COc1ccc(N)cc1N.O=S(=O)(O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A known ✓ P04350 2/20 0.46
TUBB known ✓ P07437 2/20 0.46
TUBA3C known ✓ P0DPH7 2/20 0.46
TUBA1B known ✓ P68363 2/20 0.46
TUBA4A known ✓ P68366 2/20 0.46
TUBB4B known ✓ P68371 2/20 0.46
TUBB3 known ✓ Q13509 2/20 0.46
TUBB2A known ✓ Q13885 2/20 0.46
TUBB8 known ✓ Q3ZCM7 2/20 0.46
TUBA3E known ✓ Q6PEY2 2/20 0.46
TUBA1A known ✓ Q71U36 2/20 0.46
TUBA1C known ✓ Q9BQE3 2/20 0.46
TUBB6 known ✓ Q9BUF5 2/20 0.46
TUBB2B known ✓ Q9BVA1 2/20 0.46
TUBB1 known ✓ Q9H4B7 2/20 0.46
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
MMP1 P03956 1/20 0.56
MMP2 P08253 1/20 0.56
MMP9 P14780 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL29558209 1.00 CA1 (0.56) CA1CA2MMP1MMP2MMP9
Sulfuric Acid SCHEMBL11435520 0.98 CA1 (0.54) CA1CA2MMP1MMP2MMP9
Sulfuric Acid SCHEMBL4824645 0.98 CA1 (0.54) CA1CA2MMP1MMP2MMP9
Sulfuric Acid SCHEMBL11681409 0.91 CA1 (0.55) CA1CA2MMP1MMP2MMP9
Methyl Alcohol SCHEMBL28031053 0.88 ALDH1A1 (0.59) CA1CA2MMP1MMP2MMP9
SCHEMBL15514306 0.88 ALDH1A1 (0.64) ALDH1A1HTTLMNAL3MBTL1CYP3A4
SCHEMBL29389101 0.88 ALDH1A1 (0.64) ALDH1A1HTTLMNAL3MBTL1CYP3A4
SCHEMBL212391 0.88 ALDH1A1 (0.64) ALDH1A1HTTLMNAL3MBTL1CYP3A4
Water SCHEMBL11435527 0.86 ALDH1A1 (0.61) ALDH1A1HTTLMNAL3MBTL1CYP3A4
Water SCHEMBL6445920 0.86 ALDH1A1 (0.61) ALDH1A1HTTLMNAL3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114425027-A Hair dye and preparation method thereof 广州市芊彩化妆品有限公司 2022-05-03 CN claimed
CN-110531011-A A kind of detection method of 2,4- diamino anisole sulfate GUANGZHOU GRG METROLOGY & TEST CO LTD 2019-12-03 CN claimed
CN-106225213-A Thermal coupling device control system and control method thereof in a kind of megastore water system 江苏建筑职业技术学院 2016-12-14 CN claimed
EP-0193692-B1 PROCESS FOR ASSESSING THE SURFACE STATE OF KERATINOUS FIBRES, AND COMPOSITION FOR CARRYING OUT SAID PROCESS L'OREAL (FR) 1989-04-05 EP claimed
US-4642294-A COLORIMETRIC ANALYSIS L'OREAL (FR) 1987-02-10 US claimed
US-4104021-A OXIDATION COLOR DYES COMBE INCORPORATED (US) 1978-08-01 US claimed
CN-115919663-A Hair dyeing essential oil and preparation method thereof 广州市芊彩化妆品有限公司 2023-04-07 CN disclosed
CN-114425027-A Hair dye and preparation method thereof 广州市芊彩化妆品有限公司 2022-05-03 CN disclosed
CN-110531011-A A kind of detection method of 2,4- diamino anisole sulfate GUANGZHOU GRG METROLOGY & TEST CO LTD 2019-12-03 CN disclosed
CN-110531011-A A kind of detection method of 2,4- diamino anisole sulfate GUANGZHOU GRG METROLOGY & TEST CO LTD 2019-12-03 CN disclosed
CN-110531011-A A kind of detection method of 2,4- diamino anisole sulfate GUANGZHOU GRG METROLOGY & TEST CO LTD 2019-12-03 CN disclosed
EP-2178948-B1 NOVEL POLYUREA- AND/OR POLYURETHANE-POLYORGANOSILOXANE COMPOUNDS MOMENTIVE PERFORMANCE MAT GMBH (DE) 2017-04-05 EP disclosed
US-20170027168-A1 METHODS, PRODUCTS, AND SYSTEMS RELATING TO MAKING, PROVIDING, AND USING NANOCRYSTALLINE (NC) PRODUCTS COMPRISING NANOCRYSTALLINE CELLULOSE (NCC), NANOCRYSTALLINE (NC) POLYMERS AND/OR NANOCRYSTALLINE (NC) PLASTICS OR OTHER NANOCRYSTALS OF CELLULOSE COMPOSITES OR STRUCTURES, IN COMBINATION WITH OTHER MATERIALS HEATH STEPHAN (US) 2017-02-02 US disclosed
US-4104021-A OXIDATION COLOR DYES COMBE INCORPORATED (US) 1978-08-01 US disclosed
US-4013404-A Method of dyeing hair with indolines, indoles and indazoles AMERICAN CYANAMID COMPANY (US) 1977-03-22 US disclosed
US-4008272-A OXIDATION COLOR DYES, HAIR SOCIETE ANONYME DITE: L'OREAL (FR) 1977-02-15 US disclosed
US-4004877-A Hair dye and its use CARL BREHMER & SOHN (DT) 1977-01-25 US disclosed
US-3981677-A Oxidative hair dye compositions containing N-substituted o-phenylenediamines and method for their use CLAIROL INCORPORATED (US) 1976-09-21 US disclosed
US-3970423-A PHENYLENEDIAMINE DERIVATIVES CLAIROL INCORPORATED (US) 1976-07-20 US disclosed
US-3960476-A OXIDATION BASE GHILARDI GIULIANA 1976-06-01 US disclosed