Sulfuric Acid

Sulfuric Acid

SCHEMBL4824645

COc1ccc(N)cc1N.O.O=S(=O)(O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A known ✓ P04350 2/20 0.45
TUBB known ✓ P07437 2/20 0.45
TUBA3C known ✓ P0DPH7 2/20 0.45
TUBA1B known ✓ P68363 2/20 0.45
TUBA4A known ✓ P68366 2/20 0.45
TUBB4B known ✓ P68371 2/20 0.45
TUBB3 known ✓ Q13509 2/20 0.45
TUBB2A known ✓ Q13885 2/20 0.45
TUBB8 known ✓ Q3ZCM7 2/20 0.45
TUBA3E known ✓ Q6PEY2 2/20 0.45
TUBA1A known ✓ Q71U36 2/20 0.45
TUBA1C known ✓ Q9BQE3 2/20 0.45
TUBB6 known ✓ Q9BUF5 2/20 0.45
TUBB2B known ✓ Q9BVA1 2/20 0.45
TUBB1 known ✓ Q9H4B7 2/20 0.45
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
MMP1 P03956 1/20 0.54
MMP2 P08253 1/20 0.54
MMP9 P14780 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL11435520 1.00 CA1 (0.54) CA1CA2MMP1MMP2MMP9
Sulfuric Acid SCHEMBL29558209 0.98 CA1 (0.56) CA1CA2MMP1MMP2MMP9
Sulfuric Acid SCHEMBL479725 0.98 CA1 (0.56) CA1CA2MMP1MMP2MMP9
Sulfuric Acid SCHEMBL11681409 0.89 CA1 (0.55) CA1CA2MMP1MMP2MMP9
Water SCHEMBL6445920 0.88 ALDH1A1 (0.61) ALDH1A1HTTLMNAL3MBTL1CYP3A4
Water SCHEMBL11435527 0.88 ALDH1A1 (0.61) ALDH1A1HTTLMNAL3MBTL1CYP3A4
Methyl Alcohol SCHEMBL28031053 0.86 ALDH1A1 (0.59) CA1CA2MMP1MMP2MMP9
SCHEMBL29389101 0.86 ALDH1A1 (0.64) ALDH1A1HTTLMNAL3MBTL1CYP3A4
SCHEMBL15514306 0.86 ALDH1A1 (0.64) ALDH1A1HTTLMNAL3MBTL1CYP3A4
SCHEMBL212391 0.86 ALDH1A1 (0.64) ALDH1A1HTTLMNAL3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103852539-B The detection method of azo in a kind of electronic devices and components 广州市博诺通化工技术服务有限公司 2017-03-15 CN disclosed
CN-103852539-A Method for detecting azo in electronic element KUNSHAN LUODAN BIOTECHNOLOGY CO LTD 2014-06-11 CN disclosed
US-7445877-B2 Charge transport materials having a central disulfane linkage SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-11-04 US disclosed
US-7326506-B2 Bridged charge transport materials having a central sulfur atom linkage SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-02-05 US disclosed
EP-1600821-B1 Bridged charge transport materials having a central sulfur atom linkage SAMSUNG ELECTRONICS CO LTD (KR) 2007-02-28 EP disclosed
EP-1529779-B1 Organophotoreceptor with charge transport material with two N,N,N,-trisubstituted-amino groups SAMSUNG ELECTRONICS CO LTD (KR) 2006-12-20 EP disclosed
US-20050277038-A1 Charge transport materials having a central disulfane linkage S-PRINTING SOLUTION CO., LTD. (KR) 2005-12-15 US disclosed
US-20050266329-A1 Bridged charge transport materials having a central sulfur atom linkage S-PRINTING SOLUTION CO., LTD. (KR) 2005-12-01 US disclosed
EP-1600821-A1 Bridged charge transport materials having a central sulfur atom linkage Samsung Electronics Co., Ltd. (KR) 2005-11-30 EP disclosed
CN-1702563-A Bridged charge transport materials having a central sulfur atom linkage SAMSUNG ELECTRONICS CO LTD (KR) 2005-11-30 CN disclosed
US-20050089780-A1 Organophotoreceptor with charge transport material with two N,N,N-trisubstituted-amino groups S-PRINTING SOLUTION CO., LTD. (KR) 2005-04-28 US disclosed
CN-1609719-A Organophotoreceptor with charge transport material with two n,n,n-trisubstituted-amino groups SAMSUNG ELECTRONICS CO LTD (KR) 2005-04-27 CN disclosed
EP-1148048-A2 Polyaromatic antiviral compositions PHARMACIA & UPJOHN COMPANY (US) 2001-10-24 EP disclosed
EP-1068531-A2 LIGAND SCREENING AND DESIGN BY X-RAY CRYSTALLOGRAPHY Abbott Laboratories (US) 2001-01-17 EP disclosed
US-6147116-A TOPICALLY ADMINISTERING BENZENE DERIVATIVE SUBSTITUTED WITH UREIDO-, THIOUREIDO, AND/OR SULFONAMIDO GROUPS TO TREAT HERPES PHARMACIA & UPJOHN COMPANY (US) 2000-11-14 US disclosed
EP-0973735-A2 POLYAROMATIC ANTIVIRAL COMPOSITIONS PHARMACIA & UPJOHN COMPANY (US) 2000-01-26 EP disclosed
US-5958983-A NOVEL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST HERPES, TOPICAL ADMINISTRATION THEM TO TREAT PATIENTS WITH HERPES; WORK BY INHIBITING THE INITIATION OF HERPES VIRAL DNA SYNTHESIS IN HOST CELLS PHARMACIA & UPJOHN COMPANY (US) 1999-09-28 US disclosed
WO-1999045379-A2 LIGAND SCREENING AND DESIGN BY X-RAY CRYSTALLOGRAPHY ABBOTT LABORATORIES (US) 1999-09-10 WO disclosed
WO-1999045389-A2 LIGAND SCREENING AND DESIGN BY X-RAY CRYSTALLOGRAPHY ABBOTT LAB (US) 1999-09-10 WO disclosed
WO-1998045259-A2 POLYAROMATIC ANTIVIRAL COMPOSITIONS PHARMACIA & UPJOHN COMPANY (US) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050266329-A1 Bridged charge transport materials having a central sulfur atom linkage NR2E3, NR4A2, NR2C2 TUBB4A 2059/4885TUBB 3102/4885TUBA3C 2830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.