SCHEMBL4797282

SCHEMBL4797282

O=C(NC[C@H]1CC[C@H](C(=O)O)CC1)OCc1ccc(Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
GAA P10253 1/20 0.52
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
VCP P55072 2/20 0.46
TPSAB1 Q15661 1/20 0.46
TPSD1 Q9BZJ3 1/20 0.46
TPSG1 Q9NRR2 1/20 0.46
LPAR1 Q92633 1/20 0.42
POLB P06746 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
TSHR P16473 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL594858 0.88 ALDH1A1 (0.67) ALDH1A1GAAMEN1KMT2ANPC1
SCHEMBL594857 0.88 ALDH1A1 (0.67) ALDH1A1GAAMEN1KMT2ANPC1
Potassium Ion SCHEMBL4653751 0.88 MEN1 (0.48) ALDH1A1GAAMEN1KMT2ANPC1
SCHEMBL4795836 0.87 ALDH1A1 (0.52) ALDH1A1GAAMEN1KMT2ANPC1
SCHEMBL4652521 0.87 KMT2A (0.53) ALDH1A1GAAMEN1KMT2ANPC1
SCHEMBL4654803 0.87 ALDH1A1 (0.65) ALDH1A1GAAMEN1KMT2ANPC1
Ammonia Solution, Strong SCHEMBL5846266 0.86 KMT2A (0.52) ALDH1A1GAAMEN1KMT2ANPC1
SCHEMBL4652505 0.85 ALDH1A1 (0.51) ALDH1A1GAAVCPPOLBTSHR
SCHEMBL4652511 0.85 ALDH1A1 (0.51) ALDH1A1GAAVCPPOLBTSHR
SCHEMBL4652516 0.85 ALDH1A1 (0.50) ALDH1A1GAAMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1604647-B1 Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof CHISSO CORP (JP) 2008-05-07 EP disclosed
US-20060018867-A1 Cosmetic composition and production thereof ICHIMARU PHARCOS CO., LTD 2006-01-26 US disclosed
EP-1604647-A1 Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof Ichimaru Pharcos Co., Ltd. (JP) 2005-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060018867-A1 Cosmetic composition and production thereof CUTA, PARG, TYR ALDH1A1 1854/4885GAA 35/4885MEN1 1028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.