Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5846266

Cc1ccc(COC(=O)NC[C@H]2CC[C@H](C(=O)O)CC2)cc1.N

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.52
ALDH1A1 P00352 3/20 0.52
MEN1 O00255 3/20 0.52
CYP2C9 P11712 1/20 0.52
GAA P10253 1/20 0.51
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
NAAA Q02083 1/20 0.45
VCP P55072 2/20 0.45
TPSAB1 Q15661 1/20 0.45
TPSD1 Q9BZJ3 1/20 0.45
TPSG1 Q9NRR2 1/20 0.45
TAS2R14 Q9NYV8 2/20 0.45
GRIN2B Q13224 1/20 0.43
PKM P14618 1/20 0.41
PTGIR P43119 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4652521 0.99 KMT2A (0.53) KMT2AALDH1A1MEN1CYP2C9GAA
SCHEMBL594857 0.87 ALDH1A1 (0.67) KMT2AALDH1A1MEN1CYP2C9GAA
SCHEMBL594858 0.87 ALDH1A1 (0.67) KMT2AALDH1A1MEN1CYP2C9GAA
SCHEMBL4652516 0.86 ALDH1A1 (0.50) KMT2AALDH1A1MEN1CYP2C9GAA
SCHEMBL4797282 0.86 ALDH1A1 (0.52) KMT2AALDH1A1MEN1CYP2C9GAA
SCHEMBL4795836 0.86 ALDH1A1 (0.52) KMT2AALDH1A1MEN1CYP2C9GAA
SCHEMBL4654803 0.86 ALDH1A1 (0.65) KMT2AALDH1A1MEN1CYP2C9GAA
Ammonia Solution, Strong SCHEMBL4804478 0.83 VCP (0.49) ALDH1A1GAAVCPTPSAB1TPSD1
SCHEMBL10639382 0.82 VCP (0.50) ALDH1A1GAAVCPTPSAB1TPSD1
SCHEMBL4798640 0.82 VCP (0.50) ALDH1A1GAAVCPTPSAB1TPSD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060018867-A1 Cosmetic composition and production thereof ICHIMARU PHARCOS CO., LTD 2006-01-26 US disclosed
EP-1604647-A1 Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof Ichimaru Pharcos Co., Ltd. (JP) 2005-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060018867-A1 Cosmetic composition and production thereof CUTA, PARG, TYR KMT2A 847/4885ALDH1A1 1854/4885MEN1 1028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.