Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354123 | 0.90 | LMNA (0.47) | HPGDALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL587681 | 0.85 | LMNA (0.53) | ALDH1A1TSHRLMNASMN1; SMN2POLB | |
| SCHEMBL7357706 | 0.84 | ALDH1A1 (0.48) | HPGDALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL16052055 | 0.82 | ALDH1A1 (0.58) | HPGDALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL4156159 | 0.80 | ALDH1A1 (0.72) | HPGDALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL27752273 | 0.80 | HPGD (0.72) | HPGDALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL20980883 | 0.79 | ALDH1A1 (0.54) | HPGDALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL20827449 | 0.79 | LMNA (0.48) | HPGDALDH1A1TSHRLMNASMN1; SMN2 | |
| SCHEMBL14821407 | 0.78 | CES2 (0.58) | HPGDALDH1A1TSHRLMNASMN1; SMN2 | |
| Cyclopropane Carboxylic Acid SCHEMBL4623651 | 0.78 | CES2 (0.58) | HPGDALDH1A1TSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008051017-A1 | A CLEAVAGE AGENT SELECTIVELY ACTING ON SOLUBLE ASSEMBLY OF AMYLOIDOGENIC PEPTIDE OR PROTEIN | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2008-05-02 | — | — | WO | disclosed |