Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | XIAP | P98170 | 5/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871439 | 0.81 | NAAA (0.43) | PYGLNAAAXIAPPARP1PREP | |
| SCHEMBL6216047 | 0.81 | SMN1; SMN2 (0.59) | NAAAPOLBPARP1PREPALDH1A1 | |
| SCHEMBL3932081 | 0.81 | SMN1; SMN2 (0.59) | NAAAPOLBPARP1PREPALDH1A1 | |
| SCHEMBL3932072 | 0.81 | SMN1; SMN2 (0.59) | NAAAPOLBPARP1PREPALDH1A1 | |
| SCHEMBL14195877 | 0.79 | NAMPT (0.48) | NAMPTNAAAROCK2POLBALDH1A1 | |
| SCHEMBL4870911 | 0.78 | NAAA (0.46) | NAAAXIAPPARP1PREPALDH1A1 | |
| SCHEMBL8342335 | 0.78 | XIAP (0.49) | NAAAXIAPPOLBPREPALDH1A1 | |
| SCHEMBL4802366 | 0.77 | NAAA (0.52) | NAMPTNAAAROCK2POLBALDH1A1 | |
| SCHEMBL7420278 | 0.77 | CA1 (0.46) | PYGLNAAAPREPALDH1A1GAA | |
| SCHEMBL5114897 | 0.77 | NAAA (0.44) | NAAAPARP1PREPALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361766-B2 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361766-B2 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361766-B2 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-22 | — | — | US | disclosed |
| WO-2006076569-A2 | BICYCLIC HETEROCYCLES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20060154956-A1 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154956-A1 | Bicyclic heterocycles as cannabinoid receptor modulators | CNR1, CNR2, CCKBR | PYGL 2944/4885NAMPT 2040/4885NAAA 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.