Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193321 | 0.87 | NAAA (0.52) | NAAAALDH1A1GAATLR4TSHR | |
| SCHEMBL4818956 | 0.87 | NAAA (0.52) | NAAAALDH1A1GAATLR4TSHR | |
| SCHEMBL4802366 | 0.82 | NAAA (0.52) | NAMPTNAAAPOLBROCK2ALDH1A1 | |
| SCHEMBL4797980 | 0.79 | PYGL (0.47) | NAMPTNAAAPOLBROCK2ALDH1A1 | |
| SCHEMBL21855472 | 0.77 | CA1 (0.61) | NAMPTPOLBROCK2ALDH1A1GAA | |
| SCHEMBL1718075 | 0.77 | TLR4 (0.56) | NAAAALDH1A1GAATLR4TSHR | |
| SCHEMBL8990918 | 0.73 | NAAA (0.60) | NAAACTSL | |
| SCHEMBL8990914 | 0.73 | NAAA (0.60) | NAAACTSL | |
| SCHEMBL29481093 | 0.73 | NAAA (0.60) | NAAACTSL | |
| SCHEMBL425375 | 0.72 | ALDH1A1 (0.58) | NAAAALDH1A1GAATLR4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361766-B2 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361766-B2 | Bicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-04-22 | — | — | US | disclosed |