Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.77 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ESRRB | O95718 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774227 | 0.89 | ESR1 (0.77) | ESR1ESR2MEN1KMT2ACYP3A4 | |
| SCHEMBL27277 | 0.88 | ESR1 (1.00) | ESR1ESR2MEN1KMT2ACYP3A4 | |
| SCHEMBL8031149 | 0.88 | ESR1 (1.00) | ESR1ESR2MEN1KMT2ACYP3A4 | |
| Phenol SCHEMBL29851136 | 0.86 | ESR1 (0.95) | ESR1ESR2MEN1KMT2ACYP3A4 | |
| Methane SCHEMBL16667289 | 0.86 | ESR1 (0.95) | ESR1ESR2MEN1KMT2ACYP3A4 | |
| SCHEMBL7809710 | 0.84 | MEN1 (0.72) | ESR1ESR2MEN1KMT2ACYP3A4 | |
| Phenol SCHEMBL8987629 | 0.83 | ESR1 (0.91) | ESR1ESR2MEN1KMT2ACYP3A4 | |
| SCHEMBL7917092 | 0.82 | MEN1 (0.70) | ESR1ESR2MEN1KMT2ACYP3A4 | |
| SCHEMBL23059478 | 0.82 | ESR1 (0.87) | ESR1ESR2MEN1KMT2ACYP3A4 | |
| Bicarbonate SCHEMBL19723102 | 0.82 | ESR1 (0.87) | ESR1ESR2MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790363-B2 | Polyester-polycarbonate composition and article | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-10-17 | — | — | US | disclosed |
| EP-1957561-A1 | HIGH GLASS TRANSITION TEMPERATURE COPOLYCARBONATES, METHODS OF MANUFACTURE, AND USES THEREOF | General Electric Company, (a New York Corporation) (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007064670-A1 | HIGH GLASS TRANSITION TEMPERATURE COPOLYCARBONATES, METHODS OF MANUFACTURE, AND USES THEREOF | GENERAL ELECTRIC COMPANY (US) | 2007-06-07 | — | — | WO | disclosed |