Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.91 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TYR | P14679 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | ESRRG | P62508 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL29851136 | 0.98 | ESR1 (0.95) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL27277 | 0.95 | ESR1 (1.00) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL8031149 | 0.95 | ESR1 (1.00) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| Phenol SCHEMBL5446380 | 0.93 | ESR1 (0.79) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| Methane SCHEMBL16667289 | 0.93 | ESR1 (0.95) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL4063477 | 0.89 | ESR1 (0.80) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL22335854 | 0.89 | ESR1 (0.80) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL18750 | 0.89 | ESR1 (0.80) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| SCHEMBL23059478 | 0.89 | ESR1 (0.87) | ESR1ESR2CYP3A4ALDH1A1LMNA | |
| Bicarbonate SCHEMBL19723102 | 0.89 | ESR1 (0.87) | ESR1ESR2CYP3A4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378858-B1 | Process for the preparation of branched thermoplastic polycarbonates | GEN ELECTRIC (US) | 1996-06-12 | — | — | EP | claimed |
| US-8841388-B2 | Monofunctional, bifunctional, and multifunctional phosphinated phenols and their derivatives and preparation method thereof | NATIONAL CHUNG HSING UNIVERSITY (TW) | 2014-09-23 | — | — | US | disclosed |
| CN-103122010-A | Novel phosphorus monofunctional, bifunctional and multifunctional phenols and derivatives thereof and preparation method thereof | NAT UNIV CHUNG HSING | 2013-05-29 | — | — | CN | disclosed |
| US-20130012668-A1 | MONOFUNCTIONAL, BIFUNCTIONAL, AND MULTIFUNCTIONAL PHOSPHINATED PHENOLS AND THEIR DERIVATIVES AND PREPARATION METHOD THEREOF | NATIONAL CHUNG HSING UNIVERSITY (TW) | 2013-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012668-A1 | MONOFUNCTIONAL, BIFUNCTIONAL, AND MULTIFUNCTIONAL PHOSPHINATED PHENOLS AND THEIR DERIVATIVES AND PREPARATION METHOD THEREOF | PHOSPHO1, PLCG2, PLCB3 | ESR1 176/4885ESR2 653/4885CYP3A4 965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.