Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453878 | 0.79 | ALDH1A1 (0.68) | ALDH1A1MAPTKDM4EGAATDP1 | |
| SCHEMBL11792458 | 0.65 | SMN1; SMN2 (0.59) | ALDH1A1MAPTKDM4EGAATDP1 | |
| SCHEMBL10873813 | 0.64 | GAA (0.52) | ALDH1A1MAPTKDM4EGAATDP1 | |
| SCHEMBL12235874 | 0.64 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EGAATDP1 | |
| SCHEMBL5047643 | 0.62 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EGAATDP1 | |
| SCHEMBL10408359 | 0.62 | KMT2A (0.56) | ALDH1A1MAPTKDM4EGAATDP1 | |
| SCHEMBL29286764 | 0.61 | MAPT (0.55) | ALDH1A1MAPTKDM4EGAATDP1 | |
| SCHEMBL13605317 | 0.61 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EGAATDP1 | |
| SCHEMBL4343424 | 0.61 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EGAATDP1 | |
| SCHEMBL24246437 | 0.61 | MAPK1 (0.48) | ALDH1A1MAPTKDM4EGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7331997-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-19 | — | — | US | disclosed |