Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10408359 | 0.85 | KMT2A (0.56) | ALDH1A1MAPTGAAMAPK1HSD17B10 | |
| SCHEMBL10873813 | 0.80 | GAA (0.52) | ALDH1A1POLBMAPTGAAMAPK1 | |
| SCHEMBL4343424 | 0.74 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTGAAMAPK1 | |
| SCHEMBL27298862 | 0.74 | HPGD (0.48) | ALDH1A1POLBMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL18190417 | 0.73 | POLB (0.52) | ALDH1A1POLBMAPTMAPK1TP53 | |
| SCHEMBL4347039 | 0.73 | APP (0.48) | ALDH1A1POLBMAPTGAAMAPK1 | |
| SCHEMBL3194480 | 0.72 | MAPT (0.50) | ALDH1A1POLBMAPTGAAMAPK1 | |
| SCHEMBL11332749 | 0.71 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTGAAMAPK1 | |
| SCHEMBL453878 | 0.71 | ALDH1A1 (0.68) | ALDH1A1POLBMAPTGAAMAPK1 | |
| SCHEMBL11123502 | 0.71 | SMN1; SMN2 (0.45) | ALDH1A1POLBMAPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1744720-B1 | KERATIN DYEING COMPOSITIONS CONTAINING bicyclic 5-5 heteroaromatic compounds | PROCTER & GAMBLE (US) | 2008-11-26 | — | — | EP | disclosed |