Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | IAPP | P10997 | 4/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289563 | 0.87 | CA1 (0.47) | CA1CA2CA12CA7CA9 | |
| SCHEMBL15546961 | 0.83 | ACHE (0.41) | ACHEELANESMN1; SMN2ESR1HIF1A | |
| SCHEMBL8830200 | 0.81 | ACHE (0.40) | ACHEELANESMN1; SMN2ESR1HIF1A | |
| SCHEMBL2469340 | 0.81 | ACHE (0.43) | ACHEELANESMN1; SMN2ESR1HIF1A | |
| Hydrochloric Acid SCHEMBL21519784 | 0.80 | ACHE (0.42) | ACHEELANESMN1; SMN2ESR1HIF1A | |
| SCHEMBL6060769 | 0.79 | CA1 (0.41) | CA1CA2CA12CA7CA9 | |
| SCHEMBL2671806 | 0.79 | ACHE (0.47) | CA1CA2CA12CA7CA9 | |
| SCHEMBL5199939 | 0.78 | ALDH1A1 (0.48) | CA1CA2CA12CA7CA9 | |
| Hydrochloric Acid SCHEMBL7834968 | 0.78 | ACHE (0.46) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6065085 | 0.77 | MAPT (0.44) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999095-A2 | PROCESSES FOR CONVERSION OF TYROSINE TO P-HYDROXYSTYRENE AND P-ACETOXYSTYRENE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-12-10 | — | — | EP | claimed |
| US-7402713-B2 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-22 | — | — | US | claimed |
| WO-2007103478-A2 | PROCESSES FOR CONVERSION OF TYROSINE TO P-HYDROXYSTYRENE AND P-ACETOXYSTYRENE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-09-13 | — | — | WO | claimed |
| US-20070213569-A1 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-09-13 | — | — | US | claimed |
| EP-1999095-A2 | PROCESSES FOR CONVERSION OF TYROSINE TO P-HYDROXYSTYRENE AND P-ACETOXYSTYRENE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-12-10 | — | — | EP | disclosed |
| US-7402713-B2 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-22 | — | — | US | disclosed |
| WO-2007103478-A2 | PROCESSES FOR CONVERSION OF TYROSINE TO P-HYDROXYSTYRENE AND P-ACETOXYSTYRENE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-09-13 | — | — | WO | disclosed |
| US-20070213569-A1 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213569-A1 | Processes for conversion of tyrosine to p-hydroxystyrene and p-acetoxystyrene | TH, PAH, TPST2 | CA1 2883/4885CA2 2621/4885CA12 2337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.