Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745728 | 0.91 | ALDH1A1 (0.48) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL4800824 | 0.89 | KCNH2 (0.42) | MAPTKMT2AMEN1GAAKCNH2 | |
| SCHEMBL7191685 | 0.84 | L3MBTL1 (0.49) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL11506360 | 0.84 | ALDH1A1 (0.49) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL4781890 | 0.83 | KCNH2 (0.47) | MAPTKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL20198518 | 0.81 | MAPT (0.47) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL7088249 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2PRSS1HDAC6 | |
| SCHEMBL356336 | 0.80 | L3MBTL1 (0.51) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL5023620 | 0.80 | ALDH1A1 (0.51) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL15585986 | 0.80 | SMN1; SMN2 (0.46) | KMT2ASMN1; SMN2POLBPRSS1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |